Antifungal and Anticancer Potential of Argemone mexicana L.

نویسندگان

  • Nilesh V. More
  • Arun S. Kharat
چکیده

Background: Medicinal plants are widely used to treat infectious diseases, metabolic disorders and cancer. Argemone mexicana L. (A. mexicana), commonly found on desolate land of Marathwada (Maharashtra, India) has been used to treat oral cavity infections. Methods: In this study, cold aqueous and methanolic extracts were prepared from A. mexicana stem and leaves. These extracts were tested for their antifungal and anticancer activities. The antifungal activity was tested using the agar well diffusion method, while the anticancer activity against immortalized cell lines was assessed by trypan blue assay. Results: It was observed that both cold aqueous and methanolic extracts of A. mexicana stem and leaves inhibited the growth of Mucor indicus, Aspergillus flavus, Aspergillus niger and Penicillum notatum. Antifungal activity of the extract was comparable to that of Amphoterecin-B. A. mexicana extracts had a cytotoxic effect on A549, SiHa and KB immortalized cell lines that were similar to that of berberine. Conclusion: The A. mexicana leaf and stems exhibit strong antifungal and anticancer potential.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bacillus cereus infection in stinging catfish, Heteropneustes fossilis (Siluriformes: Heteropneustidae) and their recovery by Argemone mexicana seed extract

Mass mortality of stinging catfish, Heteropneustes fossilis, was observed in a fish farm of Kulgaria, Burdwan in West Bengal, India. The cumulative mortality rates reached up to 5% of the total fish in the farm per day. The clinical signs of the affected fish showed ulcers on the skin which gradually grew in size and progressed to form ulcerous dermatitis. Clinical signs of catfish experimental...

متن کامل

Prevalence of antifungal activity of Argemone mexicana poppy

The poppy of Argemone Mexicana are high in protein, carbohydrates, lipids and minerals. They are also rich in novel alkaloids, and sterols The poppy of Argemone species contain a high concentration of berberine and sanguinarine alkaloids The alkaloids of argemone are widely used as Analgesic; Antispasmodic; Demulcent; Emetic; Expectorant; Hallucinogenic; Purgative; Sedative; Skin; WartsThe root...

متن کامل

EFFECT OF ACTIVE MOLLUSCICIDAL COMPONENETS OF ABRUS PRECATORIUS, ARGEMONE MEXICANA AND NERIUM INDICUM ON CERTAIN ENZYMES IN THE NERVOUS TISSUE OF LYMNAEA ACUMINATA

In vivo and in vitro sublethal exposure of abrin, glycyrrhizin (active component of Abrus precatorius seed and root), sanguinarine, protopine (Argemone mexicana seed) and oleandrin (Nerium indicum leaf) inhibited the acetylcholinesterase, lactic dehydrogenase, acid and alkaline phosphatase activity in the nervous tissue of Lymnaea acuminata. The succinic dehydrogenase activity in the nervous ti...

متن کامل

Bacillus cereus infection in stinging catfish, Heteropneustes fossilis (Siluriformes: Heteropneustidae) and their recovery by Argemone mexicana seed extract

Mass mortality of stinging catfish, Heteropneustes fossilis, was observed in a fish farm of Kulgaria, Burdwan in West Bengal, India. The cumulative mortality rates reached up to 5% of the total fish in the farm per day. The clinical signs of the affected fish showed ulcers on the skin which gradually grew in size and progressed to form ulcerous dermatitis. Clinical signs of catfish experimental...

متن کامل

Pharmacognostic, Physicochemical and Phytochemical Investigations on Aerial Parts of Argemone mexicana L.

Background and objectives: In India, Argemone mexicana is traditionally used against fever, wounds, worms and malaria. In Mali the efficacy and safety of “Sumafura Tiemoko Bengaly” an herbal tea based on A. mexicana aerial parts against malaria have been demonstrated. This study was aimed to investigate the pharmacognostic, physicochemical and phytochemical pa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2016